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REGENKIT PRP CELLULAR MASK 09
REGENKIT ACR CELLULAR MASK / ATS AVAILABLE IN SOUTH AFRICA DURING 2009 AND REPLACES INJECTIONS
REGENLAB® and REGENKIT® in Switzerland announced the availability of the REGENKIT CELLULAR FACIAL MASK®, another generation of platelet-rich plasma (PRP) for topical facial rejuvenation by the application of a PRP-impregnated FACIAL MASK®. Developed in Switzerland and Singapore, and reinforced by further advanced quantification studies in Cape Town, South Africa, results confirm the efficacy of the PRP-MASK. This ushers in a new era of natural facial rejuvenation by PRP and may well make the injectable format obsolete in 3-months. This is a powerful alternative to needle and needle-free mesotherapy. The patient’s own rejuvenating growth factors, derived from the patient’s autologous platelets, are used for the facial rejuvenation process and supplements the REGEN-PROCESS®. The Cellular Mask® , that is unique, will ensure by topical growth factor action, gradual improvement of skin tone, texture, radiance especially in the peri-orbital and peri-oral facial zones. This process can be enhanced by prior MDA, work that has origin in Tygerberg, Cape Town. This has a similar action to electroporation that enhances the topical absorption of PRP factors. So, good news for MDA again. Thus, potentially no need for fillers, IPL, RF or Lasers, just topical PRP rejuvenation. A natural biological rejuvenation process researched on three continents. And the process can be repeated 3 times a year and will keep a resurfaced face in shape. Patient’s refer to the process as natural facial rejuvenation by “ my cells”. Used in conjunction with MDA, LED, the REGENKIT PRP CELLULAR MASK® is ahead of all competitors, who only have injectable products. And that means pain, bruising and awful swelling, that is obviated by the REGENKIT PRP CELLULAR MASK®, which is another landmark in facial rejuvenation and amelioration of wrinkles. More details can be obtained from Antoine Turzi, CEO, Regenlab 5, rue de L’Eglise, CH-1146 Mollens, Switzerland or refer to www.regenlab.com .
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AUTOLOGOUS CONCENTRATED PLATELET-RICH PLASMA (A-ACR, c-PRP) CAN REJUVENATE THE FACE BY DERMAL BIOSTIMULATION.
REJUVENATION means to “ make someone or something look younger or lively” ( Oxford Paperback Dictionary and Thesaurus 2001). Dorland’s Illustrated Medical Dictionary provides an excellent description of rejuvenation: “( L.juverescere- to become young): a renewal of youth or of strength and vigour”. So really it does not matter what cosmetic treatment you use. As long as the client in the salon looks younger, lively and shows signs of renewal of youth, strength of vigour, then you have achieved a goal in rejuvenation. This may be achieved by a facial, microdermabrasion, massage, cosmetic creams etc. So one does not have to purchase a painfully expensive laser of IPL device, that only really gives subtle and modest skin tightening changes and needs over-servicing with costly multiple applications of light over weeks. And the possibility of scarring is excluded. A new solution is rejuvenation by the topical application of the REGENKIT PRP CELLULAR MASK®.
BRIEF OVERVIEW OF AUTOLOGOUS PLATELET-RICH PLASMA AND ACR: THIS IS THE PROCESS USED IN THE REGENKIT PRP CELLULAR FACIAL MASK®.
- Platelet-rich derived growth factors play an important role in wound healing and the regeneration ( rejuvenation) process.
- Platelet-rich plasma (PRP) is abbreviated as A-PRP or c-PRP.The PRP is applied topically in the CELLULAR FACE MASK®.
- Preparation in the side-room is possible as a high concentrate from plasma-rich plasma ( c-PRP) for clinical application. For this process the ATS blood collection tubes are available in the cellular mask kit. The kit is well designed and ready for use. No disposables are needed.
- Concentrated PRP (c-PRP) can be generated from PRP
- Platelet concentration in c-PRP is higher than the patients plasma
- TGF-beta 1 and other factors or cytokines can be checked in the c-PRP
- Dermal rejuvenation is possible via autologous cellular regeneration (ACR). The process is referred to as ACR-PRP rejuvenation. The REGEN-PRP® KIT can be used for mesotherapy. The new generation REGENKIT ACR CELLULAR MASK KIT® compliments the existing range of products, and is a must for salons and clinics.
- The REGENLAB®, ACR HARVESTING PROTOCOL consists of the following components: Special collection ATS tubes, vena puncture, collection and harvest of blood into the ATS tube ( 7 ml, venous blood), anti-coagulated whole blood, is carefully centrifuged to prevent platelet rupture.
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ABBREVIATIONS:
- PRP: Platelet- rich plasma
- A-PRP: Autologous platelet-rich plasma
- c-PRP : Concentrated platelet-rich plasma
- PPP: Platelet-poor plasma
- ACR: Autologous cellular regeneration
Complete rejuvenation of the aging human face is not achievable with currently available technologies such as RF, IPL, LED, biologicals or lasers. Aging is an irreversible process and can only be partially slowed down. Partial short-term restoration of rejuvenation or preservation is indeed an outcome that can be achieved up to about the age of 60-years at which stage deep vertical and horizontal lines, sagging, wrinkles, discolouration and mid-face ptosis become a challenge to the aesthetician. At best, almost all beauty treatments render subtle and modest results over an extended period of time and therefore there is a need for repeated treatment .
SKIN ANALYSIS PRIOR TO PHOTO-LIGHT THERAPY, TONING, SKIN TIGHTENING OR ACR/PRP NON-ABLATIVE RESURFACING
Florence Barret-Hill (2004) has shown the importance of advanced skin analysis in the salon. This is needed to lend credibility to aesthetic medicine and to your salon. A comprehensive assessment is needed prior to IPL, RF, ACR/PRP and fractional photothermolysis because a failure to do so will invariably result in poor outcome and client dissatisfaction. Basing therapy on skin ultrasound analysis alone, results in poor measured outcomes. Because ultrasound alone of the dermis ignores the following important skin characteristics ( superficial anatomy) and elements:
- Texture (renewal and desquamation of the stratum corneum). Surface texture of the epidermis must be established in a consultation prior to therapy.
- Colour (abnormal production of melanin resulting in hyper- or hypopigmentation must be established).
- Secretion (acid mantle, sebaceous and sudiferous glands).Is the skin oily or dry? What is the lipid status?
Therefore, skin diagnostic devices , as used by BOLANDCELL, are needed and the following elements need to be established:
- Oilyness of skin
- Dryness of skin, pore status
- Melanin depth (dyschromia, lentigenes, sun-spots, telangiectasis, melanoma, freckles, melasma).
- Epidermal and dermal atrophy
Underlying structured damage induced by photo-aging. Ultrasound possibly can demonstrate dermal collagen, but is inconsistent on epidermal 3D morphology, skins secretions and elastin content ( elastosis).
WHAT WILL BE THE END-POINT OF YOUR REJUVENATION TREATMENT PLAN USING IPL, ACR/PRP , RF OR LASER?
Following your skin diagnostic analysis you may have to correct:
- Skin tone by tightening the skin. This takes time and many sessions are needed as well as maintenance therapy (RF, IPL, Aesthera®, E-max®, Titan®, Fraxel®). Correcting skin wrinkles is not a quick fix affair, and there is no magic bullet. The problem is variability of results or predictability, as the speed of progressive chronological skin aging differs from person to person, with different genetic backgrounds.
- Are you trying to correct the texture of the skin? Do you want to improve skin renewal and desquamation of the stratum corneum? Consider glycolic acid peels, microdermabrasion and light emitting diodes (LED). In your rejuvenation endeavours you will be trying to improve excess keratinisation, loss of structural integrity leading jowls and sagging, especially of the lower face and mandibular areas, address loss of resiliency and adhesion (fibroblast and keratinocyte dysfunction) and improving glycation (see Barrett-Hill, 2004).
- Does your client present with skin colour problem (pigmentation, vitiligo, rosacea, telangiectasis grades 1-5, melasma, cloasma or lentignes)? You will be tested as most treatments give variable results in this category. This includes the use of IPL and fractional photothermolysis. No quick fix again. And recurrence of the pigment is possible, the moment the client is re-exposed to sunlight. So sunscreens, during and after photo-light therapy is critical. Melasma is tricky to treat and recurrence is common, especially in the hands of inexperienced doctors. This is also the case with freckles. Cosmelan® has been available for a number of years, but BOLANDCELL have found the product unaffordable and results very variable, with no response in many clients. These results have been confirmed by others and are available on the Internet.
- Will you be treating combination of 1-3, including a secretion problem? Are you dealing with a deficient acid mantle, impaired lymphatic system, skin atrophy, thinning and acne? Will your treatment be directed at epidermal lipids, sebaceous or sudiferous secretions or restoration of glycosaminoglycans (see Barrett-Hill, 2004)?
- Do you think the skin disorder you are treating in front of you (i.e. photoaging, vertical and horizontal crepe lines, fine line, sagging of the chin, pigmentation, creasing of the décolleté), is permanent or temporary?
- What are your primary priorities? Do you want to treat the pigmentation, crowfeet wrinkles or vertical/horizontal crepe lines affecting the face, chin and décolleté? Or do you just treat? Both are testing areas for the therapist in the following respects. The dyschromia may well respond initially, but melasma will return. Hyper-pigmentation does not respond in all cases to Cosmelan®, and the process is very impractical and drawn out. Not to talk about the cost. At best, whatever machine is used (IPL, LED or fractional laser), a 68.5% improvement in wrinkles will be detectible at 12 weeks. Mid-face ptosis is different to treat in persons older than 60-years. Skin tightening is not always easy to achieve, and it does not occur after only one treatment. Loss of structural (collagen) integrity will test the best of therapists, and often one has to resort to a filler. Botox after 60-years renders generally poor results, and money is wasted. Correction of the lymphatics with the structural integrity is important (see Barrett-Hill, 2004). Knowledge of all these elements, including background skin histology, is important so that your client can enjoy maximum response in the shortest possible time. Aspirations of the client must be determined and it may be required to tell them that it is only possible to achieve one level of improvement in the skin at the time. No guarantees can be given and multiple treatments (including maintenance therapy) are needed to give a gradual and subtle effect. In depth knowledge of ECM, glycosaminoglycans, skin histology and physiology and light physics is needed if one gets to get any results. In many cases cosmetic surgery is far better than aesthetic approaches and the results are more durable
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NEW FACIAL CELL THERAPY WITH AUTOLOGOUS CONCENTRATED PLATELET-RICH PLASMA (PRP) AVAILABLE IN AESTHETICS CLINICS IN SOUTH AFRICA. REGENLAB PROCESS.THE REGENKIT ACR CELLULAR MASK®
REGENLAB-PRP PROCESS® has now superseded the use of Isolagen®, as a leading biostimulatory method in South Africa to rejuvenate the aging face with the clients own enriched plasma. Cell-therapy for the for-seeable future is out. Isolagen® and Restorelle® technologies utilized the patients own cultured dermal fibroblasts to address facial wrinkles. Because of high production and transport costs, cell therapy with living fibroblasts became unaffordable, obsolete and production ceased. Restorelle® was initially championed at Stellenbosch, and no viable equivalent has emerged. The hiatus left was filled by REGENLAB® PRP, a patented process, and the rejuvenation results have proven superior to those of Isolagen®. Another advantage is that REGENLAB® PRP is far cheaper, and can be generated in the doctor’s rooms within 5 to 10 minutes from a small blood specimen obtained from the client undergoing facial rejuvenation. Scientific testing of other A-PRP or c-PRP tubes have proved inferior to REGENLAB® Technology. Plain, unspecified tubes used off the shelf, and used in an uncontrolled fashion have shown pathetic platelet-yield and no measurable GF. The availability of the REGENKIT ACR CELLULAR MASK® has changed everything and the playing fields of rejuvenation.
REGENLAB-PRP® PROCESS AND REGENLAB CELLULAR MASK® is state-of-the art technology, CE marked and provides the patient with the best enriched plasma, including platelet count and growth factor analysis. For the moment this is the best performance product and A-PRP technology available on the market, with predictable efficacy and measured outcomes. This has been verified by academic units and BOLANDCELL. This success has been enhanced with ongoing doctor-education in the use of A-PRP or c-PRP, including planned workshops, and hands-on training under supervision, country-wide. This initiative has been increased to ensure consistent results and to ensure patient safety.
“REGENLAB-PRP® PROCESS” is a valuable and safe adjunct to attain cosmetic facial enhancement, by the biological route, one-off, with minimal risk and is popular for non-surgical skin rejuvenation. Many clients request to rejuvenate themselves with their own plasma, instead of traumatic thermal light, lasers, IPL and RF. These modalities, including fractional photo-thermolysis, are cost ineffective, require multiple passes over weeks and render invariable and non-lasting skin rejuvenation. In some clients scarring is a problem, together with post inflammatory hyper-pigmentation.
WHAT AUTOLOGOUS REGENLAB PRP® ( AUTOLOGOUS PLATELET RICH PLASMA) OFFERS REGARDING FACIAL REJUVENATION. “THE REGENLAB PROCESS”.
- Quantifiable improvement of skin complexion with visible changes noticeable in 3-4 weeks-especially forehead, cheeks, neck and back of hands
- A-PRP or c-PRP is not a volumetric filler, but biological cell therapy with your own cells and enriched plasma
- Facial soft tissue augmentation without synthetic filler or animal products
- No need for costly lasers, IPL, or RF
- No need for fat transfer operations or face lifts
- A Cellular Mask® allows topical absorption of autologous platelet-derived factors: in this way injections are remove
HOW IS FACIAL AUGMENTATION AFFECTED WITH REGENLAB® A-PRP
- Augments the dermis and epidermis by enhancing the growth of keratinocytes, fibroblasts and deposition of collagen. This improves skin tone, texture and colour.
- One-off treatment, negligible down time, A-PRP or c-PRP can ameliorate mild to moderate skin changes but needs redoing 6-12 monthly because of the ongoing chronological aging process and senescence of fibroblasts that eventually stall forming collagen and elastin due to age-exhaustion. Although very effective, the “REGEN PROCESS” is also non-permanent rejuvenation and maintenance treatment is needed to combat ongoing aging. There is no non-surgical procedure that can match the brilliant results of a facelift at 5 and 10 years. The “REGEN PROCESS” is an excellent adjunct to soft tissue facial rejuvenation but is not a magic bullet for the amelioration of deep creases, folds, pigmentation, elastosis, jowls and deep forehead vertical lines. Clients tend to forget the aging process continues unabated and that the results of non-invasive treatments such as laser, IPL and RF only last for about 6 months. The “REGEN PROCESS” does offer something special , because the patients are plasma is used for the enhancement of facial macro-aesthetics. The following areas on the face are selected for CELLULAR MASK® by the “REGEN PROCESS”
- Forehead
- Glabella crease
- Malar and cheek area
- Periorbital and perioral zones ( including lower lid)
- Nasolabial and nasolabial folds
INVARIABLE OR NO RESPONSE TO “THE REGEN” PROCESS OR ACR INCLUDE:
- Alcohol abuse
- Cigarettes
- Genetics and rapid natural chronological aging with line formation
- Advanced solar aging
- Advanced hyperpigmentation
- Advanced and irreversible facial changes: type iii and iv face
- Deep vertical forehead lines
- Telangiectasis of the cheeks and nose associated with plethora
- Deep perioral lines ( marionette lines)
- Persons with underlying systemic disorder
CONTRAINDICATIONS TO THE “REGEN PROCESS” OR ACR.
- Facial cancer, past and present. This includes SCC, BCC and melanoma
- Systemic cancer, chemotherapy, steroid therapy
- Dermatological diseases affecting the face ( ie porphyria)
- Blood disorders and platelet abnormalities
- Anticoagulation therapy
- Certain herbal products
- Aspirin or anti-platelet agents
- Platelet dysfunction syndrome, critical thrombocytopenia, hypofibrinogenaemia, haemodynamic instability, sepsis, acute and chronic infections, chronic liver disease, aspirin and possibly vitamin E consumption ( Source: REGENLAB, Mollen, Switzerland).These contraindications are now largely of academic importance with the use of topical PRP, and the Cellular Facial Mask
SAFETY OF THE REGEN PLASMA PROCESS OF FACIAL REJUVENATION WITH AUTOLOGOUS PLATELET-RICH PLASMA AND THE REGENKIT CELLULAR MASK®
It is safe treatment because autologous ( your own, or “ my cells”) plasma is used. No injections are used, so no swelling follows from needle punctures.
MODUS OPERANDI OF THE REGEN PROCESS OF FACIAL REJUVENATION BY BIOSTIMULATION AND PRP FACIAL MASK “MESOTHERAPY”.
- Step 1: Your doctor should do an advanced skin analysis , such at BOLANDCELL, that measures skin morphology and function that allows planning of treatment, and facilitates follow-up of the client. Time: 30 minutes. BOLANDCELL uses advanced academic skin technology to achieve these aims.
- Step 2: Choose a doctor that you can trust. Discuss your concerns and problems. Obtain proper advice and have a sensible discussion.
- Step 3: Have a positive outlook, and realistic goals. The aging process is an ongoing process and cannot be reversed despite what some doctors claim. Some lesions on the face are very difficult to treat, especially pigmentation, and recurrence is often seen by academic doctors. Some non-invasive apparatus and devices have no effect at all and waste time and money.
- Step 4: The “REGEN PROCESS” has a very low side-effect profile because your own plasma is used. Tell the doctor about your allergies and pill intake ( also herbs!!)
- The cellular mask containing PRP, is applied to the face
THE “REGEN PROCESS”:
- Doctor takes a sample of venous blood from your arm
- Blood is placed in a special REGENLAB Collection Tube and the PRP is processed. This now takes 5 minutes. Other tubes render inferior levels of PRP, and poor GF stimulation, with invariable facial rejuvenation or no response. Scientific publications confirm this as well as comprehensive assessment and quantification by BOLANDCELL. If any, unproven tubes are used, you will waste your time and money, because very poor quality PRP will be generated.
- PRP generation via the REGEN PROCESS takes 5 minutes in a side room and is an accepted process.
- No injections are needed and only topical REGENKIT FACIAL CELLULAR MASK® is used
REGENLAB DETAILS: 5, rue de l’ eglise, 1146 Mollens VD, Switzerland. Internet details: www.regenlab.com., info@ regenlab.com.
Disclaimer. Bolandcell does not supply any cosmetic, aesthetic or therapeutic information or advice regards rejuvenation treatment options. These must be discussed between the client and the resident health care professional/ aesthetician, preferably a medical doctor, that is resident on-site and responsible for logistic operations, rejuvenation options and outcomes. Dermatologists and plastic surgeons, experienced in this field, should be consulted more often, because they are specialists in skin disorders. The Dermatology and Plastic Surgery Associations of South Africa can be consulted for advice regarding any aesthetic interventions.
BOLANDCELL ACADEMIC REFERENCES
- Du Toit DF et al. Shoulder surgeon…. International Journal of Shoulder Surgery. 2007.1: 87-95. ( details on platelet-rich plasma) www.internationalshoulderjournal.org.
- Du Toit DF et al. Soft and hard-tissue augmentation…. International Journal of Shoulder Surgery. 2007.1: 64-73. ( details on platelet-rich plasma) www.internationalshoulderjournal.org.
- www.acr-prp.com ( details on REGENLAB and REGENKIT).
- Man D et al. The use of platelet-rich plasma…. Plastic and Reconstructive Surgery. 107: 229-23. www.plasreconsurg.com
- Marx RE et al. Platelet-rich plasma…..Oral Surgery, Oral Medicine.. 1998:1. pt.wkhealth.com ( See Prof Marx’s textbook devoted to the use of PRP, 2005)
- Dugrillon A et al. Autologous concentrated platelet-rich plasma….. International Association of Oral and Maxillofacial Surgeons. 6 November 2002 on line. www.sciencedirect.com
Posted 10th December 2008. Cape Town. Biomed-rated International Specialist.
 
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